Inhibition of Pendrin by a small molecule reduces Lipopolysaccharide-induced acute Lung Injury

Conclusions: A novel pendrin inhibitor, YS-01, suppressed lung injury in LPS-induced ALI mice and our data provide a new strategy for the treatment of inflammatory airway diseases including sepsis-induced ALI.

Source: Theranostics - October 3, 2020 Category: Molecular Biology Authors: Eun Hye Lee, Mi Hwa Shin, Mia Gi, Jinhong Park, Doona Song, Young-Min Hyun, Ji-Hwan Ryu, Je Kyung Seong, Yoon Jeon, Gyoonhee Han, Wan Namkung, Moo Suk Park, Jae Young Choi Tags: Research Paper Source Type: research