[Neurological complications of hepatitis C infections].
[Neurological complications of hepatitis C infections].
Nervenarzt. 2020 Oct 01;:
Authors: Kleefeld F, Arendt G, Neuen-Jacob E, Maschke M, Husstedt I, Obermann M, Schmidt H, Hahn K, Deutsche Gesellschaft für Neuro-AIDS und Neuro-Infektiologie (DGNANI)
Abstract
Chronic hepatitis C virus (HCV) infection is a highly prevalent systemic disease, which can cause a variety of neurological complications. The HCV-associated symptoms can be differentiated into central and peripheral nervous systems as well as the musculature. Important pathomechanisms are HCV-associated autoimmunity (e.g. mixed cryoglobulinemia with polyneuropathy) and direct neurotoxic effects of the virus (e.g. HCV-associated cognitive deficits). Distal symmetric polyneuropathies, small fiber neuropathies and cognitive deficits are the most prevalent neurological manifestations. Furthermore, HCV infection is a risk factor for ischemic and hemorrhagic stroke as well as Parkinson's disease. As HCV infection has become a permanently curable disease in >90% of patients, early identification and antiviral treatment of HCV positive patients is of utmost importance.
PMID: 33001263 [PubMed - as supplied by publisher]
Source: Der Nervenarzt - Category: Neurology Authors: Kleefeld F, Arendt G, Neuen-Jacob E, Maschke M, Husstedt I, Obermann M, Schmidt H, Hahn K, Deutsche Gesellschaft für Neuro-AIDS und Neuro-Infektiologie (DGNANI) Tags: Nervenarzt Source Type: research
More News: Brain | Hemorrhagic Stroke | Hepatitis | Hepatitis C | HIV AIDS | Ischemic Stroke | Neurology | Parkinson's Disease | Stroke