Spread through air spaces (STAS) in invasive mucinous adenocarcinoma of the lung: Incidence, prognostic impact, and prediction based on clinicoradiologic factors

ConclusionsSTAS was associated with reduced OS and was a borderline independent poor prognostic factor in IMA. IMA with STAS was associated with older age and presence of lobulated and spiculated margins on CT scan.Key pointsSignificant findings of the studyCompared with other subtypes, IMA shows a higher incidence of STAS, which is an independent poor prognostic predictor even in IMA. Lobulated and spiculated margins on CT are associated with STAS.What this study addsConsidering that STAS can carry the potential for aerogenous metastasis, predicting STAS using preoperative surrogate CT imaging is desirable to avoid limited resection.

Source: Thoracic Cancer - September 24, 2020 Category: Cancer & Oncology Authors: Min A. Lee, Jun Kang, Ho Yun Lee, Wooil Kim, Insuk Shon, Na Young Hwang, Hong Kwan Kim, Yong Soo Choi, Jhingook Kim, Jae Ill Zo, Young Mog Shim Tags: ORIGINAL ARTICLE Source Type: research