Pleural effusion. An unfamiliar presentation of ABPA.

We report the case of a 17-year-old male who presented with complaints of fever, cough and increasing shortness of breath for 3 weeks. Patient had breathlessness with seasonal variation. Patient had right lower lobe consolidation with pleural effusion which did not respond to antibiotics. Pleural fluid was exudate with neutrophilic predominance and low ADA. Skin prick test for Aspergillus fumigatus was positive, both total IgE and specific IgE against Aspergillus fumigatus were raised. PMID: 32945640 [PubMed - as supplied by publisher]
Source: Monaldi Archives for Chest Disease - Category: Respiratory Medicine Tags: Monaldi Arch Chest Dis Source Type: research

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Abstract A young Indian man presented elsewhere with a short history of haematuria and cough. Investigations revealed renal and pulmonary lesions. Histopathology of these lesions was reported as mucormycosis. He consulted us two months after onset of symptoms, asymptomatic and clinically well, having received no treatment. In view of clinico-histopathological discordance, a review of the biopsy slides was advised but the patient refused further work-up at that time. One week later, however, he was admitted with left hemiparesis. Brain imaging showed an abscess. He underwent surgical excision of the brain abscess a...
Source: Tropical Doctor - Category: Tropical Medicine Authors: Tags: Trop Doct Source Type: research
Nurhayat Yakut, Eda Kepenekli Kadayifci, Ela Erdem Eralp, Yasemin GokdemirLung India 2020 37(2):161-163 Allergic bronchopulmonary aspergillosis (ABPA) is recognized as a rare, progressive, allergic disorder in patients with cystic fibrosis (CF) and asthma. Treatment of ABPA mainly includes systemic corticosteroids (CSs) and antifungal agents. Here, we report posaconazole treatment in a 9-year-old male child with ABPA and also review the literature on antifungal management of ABPA. The child with CF was admitted to the emergency room with complaints of fever, productive cough, and acute dyspnea. Auscultation of the lungs r...
Source: Lung India - Category: Respiratory Medicine Authors: Source Type: research
Rationale: Behçet's disease (BD) is an inflammatory disease that leads to multisystemic immune dysfunction and that involves pulmonary system alterations. Patient concerns: A 26-year-old woman presented with dull right chest pain for 30 days and intermittent cough with expectoration for 5 days. She had a history of recurrent oral ulcer and constitutional rash 2 months prior. Diagnoses: The patient was diagnosed with BD complicated by IPA and Aspergillus auriculatus infection. Interventions: The patient was administered itraconazole oral solution (200 mg b.i.d) to treat the fungal infection. After a diag...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Publication date: Available online 22 January 2020Source: Journal de Mycologie MédicaleAuthor(s): Arghadip Samaddar, Anuradha Sharma, Twishi ShrimaliAbstractAcrophialophora fusispora is a soil-borne fungus rarely implicated in human infections. Here, we report a case of pulmonary infection due to A. fusispora in a 59-year-old male who presented with productive cough and gradually progressive dyspnoea for 20 days. He had a past history of pulmonary tuberculosis and was a known case of chronic obstructive pulmonary disease for past five years. He was diagnosed with mixed connective tissue disease and had been receivin...
Source: Journal of Medical Mycology - Category: Biology Source Type: research
This report describes a patient who was diagnosed with ABPA and soon developed PTE. Patient concerns: A 64-year-old man was diagnosed with ABPA in hospital for recurrent fever with cough. Two months later, the patient was readmitted to the hospital because of PTE. Diagnoses: ABPA was diagnosed during the first hospitalization, and laboratory tests showed an increase in serum IgE and Aspergillus fumigatus-specific IgG. Sputum culture suggested A. fumigatus and high-resolution computed tomography (HRCT) showed inflammation of both lungs and central bronchiectasis. During the second hospitalization, the patient's chest ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
ConclusionsIPA is a potentially lethal complication after HT. Early diagnosis and prompt initiation of aggressive treatment are the cornerstone of better survival.ResumoIntroduçãoA infeção continua a ser uma complicação major nos recipientes para transplante cardíaco (TC), causando cerca de 20% de mortes no primeiro ano após o transplante. Nestes doentes, o Aspergillus species pode levar a várias apresentações clínicas incluindo a aspergilose pulmonar invasiva (API), com uma mortalidade elevada (53% a 78%).ObjetivosEstabelecer as caracter&i...
Source: Revista Portuguesa de Cardiologia - Category: Cardiology Source Type: research
We report an unusual case of a patient with persistent cough and dyspnoea in the context of prior chemoradiotherapy for primary lung cancer who was subsequently found to have invasive tracheobronchial aspergillosis of the distal trachea and proximal of right main bronchus. Invasive tracheobronchial aspergillosis is a rare disease with most reported cases in the literature occurring in immunocompromised hosts. We report an unusual case of a patient with persistent cough and dyspnoea in the context of prior chemoradiotherapy for primary lung cancer. Chest computed tomography (CT) demonstrated an abnormal soft tissue mass sur...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
Chronic pulmonary aspergillosis (CPA) complicates treated pulmonary tuberculosis (TB), with high 5-year mortality. We measured CPA prevalence in this group. 398 Ugandans with treated pulmonary TB underwent clinical assessment, chest radiography and Aspergillus-specific IgG measurement. 285 were resurveyed 2 years later, including computed tomography of the thorax in 73 with suspected CPA. CPA was diagnosed in patients without active TB who had raised Aspergillus-specific IgG, radiological features of CPA and chronic cough or haemoptysis. Author-defined CPA was present in 14 (4.9%, 95% CI 2.8–7.9%) resurvey patie...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Respiratory infections and tuberculosis Original Articles: Infection and tuberculosis Source Type: research
We report a 9-year- and 6-month-old girl who complained of chronic cough and recurrent wheeze for 2 months. Diagnosis: Bronchialithiasis were found under bronchoscope. Pathologic examination revealed aspergillosis. Interventions: The stone and surrounding granulation tissue were removed using a bronchoscope and the patient was treated with antifungal therapy. Outcomes: The patient was in good general health without any clinical symptoms during the follow-up period. Lessons: Pulmonary Aspergillus infection can cause bronchiolithiasis. Stones were removed under bronchoscope, and anti-Aspergillus therapy was effective.
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Chronic pulmonary aspergillosis (CPA) complicates pulmonary tuberculosis (TB). 5-year mortality is 50-85%. Prevalence is estimated at 1.3 million cases worldwide, but had not been measured. We have completed the first survey of CPA prevalence and the first survey of residual CT thorax and chest X-ray (CXR) pathology in an African population with treated TB.CT thorax is infrequently available in resource-poor settings. We calculate the accuracy of CXR for identification of CPA and CT-proven pathology.285 patients with treated TB were assessed in 2012 and 2014. Each underwent repeat clinical assessment, CXR and Aspergillus-s...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
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