Psychometric Data Linking Across HIV and Substance Use Cohorts

AbstractPsychometric data linking of psychological and behavioral questionnaires can facilitate the harmonization of data across HIV and substance use cohorts. Using data from the Collaborating Consortium of Cohorts Producing NIDA Opportunities (C3PNO), we demonstrate how to capitalize on previous linking work with a common linked depression metric across multiple questionnaires. Cohorts were young men who have sex with men (MSM), substance-using MSM, HIV/HCV cocaine users, and HIV-positive patients. We tested for differential item functioning (DIF) by comparing C3PNO cohort data with general population data. We also fit a mixed-effects model for depression, entering HIV-status and recent opioid/heroin use as fixed effects and cohort as a random intercept. Our results suggest a minimal level of DIF between the C3PNO cohorts and general population samples. After linking, descriptive statistics show a wide range of depression score means across cohorts. Our model confirmed an expected positive relationship between substance use and depression, though contrary to expectations, no significant association with HIV status. The study reveals the likely role of cohort differences, associated patient characteristics, study designs, and administration settings.
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research

Related Links:

This study will test MME against treatment as usual (TAU) among pregnant mothers diagnosed with HIV and their infants. Outcomes will be assessed during pregnancy and 16  weeks postpartum. Women who meet eligibility criteria are assigned to MME or TAU. Women assigned to MME are grouped with others with similar estimated delivery dates, completing up to eight intervention group sessions scheduled before week 36 of their pregnancies. Primary outcomes among mothers in clude (i) reducing self-stigma, which is hypothesized to mediate improvements in (ii) psychological outcomes (quality of life, depression and social functio...
Source: Trials - Category: Research Source Type: clinical trials
.
Source: AIDS Care - Category: Infectious Diseases Authors: Source Type: research
Introduction: Smoking, low education, obesity, and depressive symptoms are all associated with HIV health status, increased blood pressure, and inflammation, and constitute a syndemic burden that may contribute to poor health outcomes. The current study examined syndemic burden and health outcomes among women living with HIV. Methods: Women were participants enrolled in the Women's Interagency HIV Study. Outcomes included blood pressure, HIV health status (HIV-1 RNA viral load and CD4+ T-cell counts), and IL-6. Syndemic burden was defined as a count variable of low education, obesity, cigarette use, and depressive sym...
Source: AIDS - Category: Infectious Diseases Tags: Epidemiology and Social Source Type: research
Conclusion: In people living with HIV with neurological/neurocognitive symptoms, peripherally effective dual therapy can show CSF virosuppression, inflammation, neuronal and astrocyte integrity and neurocognition comparable to triple therapy.
Source: AIDS - Category: Infectious Diseases Tags: CLINICAL SCIENCE Source Type: research
TUESDAY, Sept. 29, 2020 -- Isolation due to the pandemic and failure to get hearing aids checked has fueled anxiety, depression and more hearing loss for many seniors. " This has been a very difficult time as senior facilities and individuals try to...
Source: Drugs.com - Daily MedNews - Category: General Medicine Source Type: news
Conclusions The experiences of participants revealed that the presence of comorbid psychological symptoms can influence the experience of hearing loss and audiological rehabilitation. These findings have implications for how audiological rehabilitation is provided to ensure optimal outcomes for adults with hearing loss and comorbid psychological symptoms. Supplemental Material https://doi.org/10.23641/asha.12985955. PMID: 32976041 [PubMed - as supplied by publisher]
Source: American Journal of Audiology - Category: Audiology Authors: Tags: Am J Audiol Source Type: research
Major depression is believed to affect treatment adherence and overall quality of life (QoL) of people living with HIV/AIDS (PLWHA). Comorbid major depression contributes to a two-fold higher risk of mortality...
Source: BMC Psychiatry - Category: Psychiatry Authors: Tags: Research article Source Type: research
CONCLUSION: Information about the impact of epidemics on parents and children is relevant to policy makers to aid them in developing strategies to help families cope with epidemic/pandemic-driven adversity and ensure their children's healthy development. PMID: 32980318 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - Category: Pediatrics Authors: Tags: J Pediatr (Rio J) Source Type: research
This study found that a considerable proportion of young people with HIV/AIDS had suicidal ideation and attempt , suggesting the urgent needs of intervention strategies to relieve the suffering and possibly prevent death due to suicide.
Source: Psychiatric Quarterly - Category: Psychiatry Source Type: research
DiscussionWe will assess feasibility and acceptability through questionnaires and adherence to TCQ. We will assess preliminary associations with symptoms such as depression, anxiety, social support, chronic HIV-related fatigue, and clinical outcomes. These will be described through proportions, means, and changes over time through graphing techniques. Outcomes will be assessed at baseline, at post-intervention, and at 3  months follow-up. These preliminary analyses also will provide information necessary to estimate effect size and power needed for a larger clinical trial.Trial registrationClinicalTrials.govNCT0384052...
Source: Trials - Category: Research Source Type: clinical trials
More News: Depression | HIV AIDS | Infectious Diseases | Psychology | Statistics | Study