Nuclear receptor FXR impairs SK-Hep-1 cell migration and invasion by inhibiting the Wnt/ β-catenin signaling pathway.

In conclusion, these results indicated that FXR may suppress SK-Hep-1 cell invasion and metastasis by suppressing the Wnt/β-catenin signaling pathway. The current study provided novel insight into the diagnosis and treatment of liver cancer. PMID: 32934729 [PubMed]
Source: Oncology Letters - Category: Cancer & Oncology Tags: Oncol Lett Source Type: research