Laxative Use and Change in Estimated Glomerular Filtration Rate in Patients With Advanced Chronic Kidney Disease

Constipation is highly prevalent in advanced chronic kidney disease (CKD), due in part to dietary (e.g., fiber) restrictions, and is often managed by laxatives; however, the effect of laxative use on kidney function in advanced CKD remains unclear. We aimed to examine the association of laxative use with longitudinal change in estimated glomerular filtration rate (eGFR) in patients with advanced CKD.

Source: Journal of Renal Nutrition - September 16, 2020 Category: Urology & Nephrology Authors: Keiichi Sumida, Ankur A. Dashputre, Praveen K. Potukuchi, Fridtjof Thomas, Yoshitsugu Obi, Miklos Z. Molnar, Justin D. Gatwood, Elani Streja, Kamyar Kalantar-Zadeh, Csaba P. Kovesdy Tags: Original Research Source Type: research