Predictors and Mechanisms of Atrial Fibrillation in Patients with Hypertrophic Cardiomyopathy

Atrial fibrillation (AF) in hypertrophic cardiomyopathy (HC) is associated with significant symptomatic deterioration, heart failure and thromboembolic disease. There is a need for better mechanistic insight and improved identification of at risk patients. We used CMR to assess predictors of AF in HC, in particular the role of myocardial fibrosis. Consecutive patients with HC referred for CMR 2003-2013 were prospectively enrolled. CMR parameters including left ventricular volumes, presence and percentage of late gadolinium enhancement in the left ventricle (%LGE) and left atrial volume index (LAVi) were measured.

Source: The American Journal of Cardiology - September 15, 2020 Category: Cardiology Authors: Claire E Raphael, Alphonsus C Liew, Frances Mitchell, Gajen Sunthar Kanaganayagam, Elisa Di Pietro, Simon Newsome, Ruth Owen, John Gregson, Robert Cooper, Fouad R Amin, Peter Gatehouse, Vassilis Vassiliou, Sabine Ernst, Rory O'Hanlon, Michael Frenneaux, D Source Type: research