De-Epithelialized Heterotopic Tracheal Allografts without Immunosuppressants in Dogs: Long-Term Results for Cartilage Viability and Structural Integrity.

CONCLUSIONS: Epithelium-decellularized tracheal allografts with chondrocyte viability can be achieved by combined use of a detergent and organ preservation solution, which showed satisfactory cartilage viability and structural integrity after long-term heterotopic transplantation. Further studies on orthotopic transplantation are needed to assess the feasibility of allografts in reconstructing long segmental tracheal defects. PMID: 32911959 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32911959?dopt=Abstract

Source: The Annals of Otology, Rhinology, and Laryngology - September 9, 2020 Category: ENT & OMF Authors: Cui P, Liu P, Li S, Ma R Tags: Ann Otol Rhinol Laryngol Source Type: research