Deep brain stimulation of the internal globus pallidus does not affect the limbic circuit in patients with Parkinson ’s disease: a PET study

ConclusionThe present study confirmed that GPi-DBS is an effective treatment in patients with advanced PD, owing to metabolic changes in the areas involved in motor execution. The absence of relative metabolic decrease in the limbic circuit and the few changes affecting the associative circuit could explain why GPi-DBS is cognitively safe.
Source: Journal of Neurology - Category: Neurology Source Type: research