Assessment of Incubation Period of Cutaneous Leishmaniasis due to Leishmania major in Tunisia.

Assessment of Incubation Period of Cutaneous Leishmaniasis due to Leishmania major in Tunisia. Am J Trop Med Hyg. 2020 Sep 08;: Authors: Aoun K, Kalboussi Y, BenSghaier I, Souissi O, Hammami H, Bellali H, Bouratbine A Abstract The period between the infective sandfly bites and appearance of cutaneous leishmaniasis (CL) lesions is still hypothetical and little studied. This work aimed at assessing the incubation time of zoonotic CL (ZCL) due to Leishmania major using a standardized methodology. The retrospective analysis used the epidemiological, clinical, and biological information available in the database recording all the CL cases diagnosed at the Parasitology Department of the Pasteur Institute of Tunis during 2015-2019. It allowed for the selection of 92 privileged observations 1) of confirmed CL cases with presentation suggestive of ZCL form 2) living in northern regions free of ZCL 3) with a single infective trip of less than a week to ZCL foci during transmission season and 4) with accurate dates of travel and onset of lesions. Incubation length computed in this population ranged from 1 to 21 weeks, with a median of 5 weeks (interquartile range: 3-8.5 weeks). PMID: 32901597 [PubMed - as supplied by publisher]
Source: The American Journal of Tropical Medicine and Hygiene - Category: Tropical Medicine Authors: Tags: Am J Trop Med Hyg Source Type: research