Anatomic-Functional (Perfusion-Based) Magnetic Resonance Imaging Follow-up in Patients With Rheumatoid Arthritis Treated With Anti–Interleukin 6 Antibodies: A Comparison With Clinical Scores and Serologic Data

Conclusions: Considering the temporal change of perfusion-derived MRI parameters (transfer constant, blood plasma volume fraction, relative enhancement, and rate of early enhancement) as well as morphologic MRI parameters (synovial volume measurements), a quantifiable assessment of response to TCZ therapy in rheumatoid arthritis seems possible at an even earlier time point compared with clinical assessment scores, whereas serologic biomarkers proved nonspecific in this respect.
Source: Journal of Computer Assisted Tomography - Category: Radiology Tags: Musculoskeletal Imaging Source Type: research