A Type 2 Deiodinase-Dependent Increase in Vegfa Mediates Myoblast-Endothelial Cell Crosstalk During Skeletal Muscle Regeneration.

CONCLUSION: <i>Dio2</i> loss in the muscle stem cell impairs muscle stem cell-endothelial cell crosstalk <i>via</i> changes in the T3-responsive gene <i>Vegfa</i>, leading to downstream impairment of endothelial cell function <i>in vitro</i> and <i>in vivo</i>. PMID: 32787533 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research