IGF-1 affects the development of myocarditis in LDL-R knockout mice by inhibiting peritoneal infiltration of macrophages.

CONCLUSIONS: IGF-1 expression is increased in myocarditis. The downregulation of IGF-1 expression inhibits macrophages infiltration, reduces the expression of MIF and inflammatory factors, and improves myocarditis injury. PMID: 32767338 [PubMed - in process]
Source: Methods of Information in Medicine - Category: Information Technology Authors: Tags: Eur Rev Med Pharmacol Sci Source Type: research