Resolvin E1 protects against doxorubicin-induced cardiotoxicity by inhibiting oxidative stress, autophagy and apoptosis by targeting AKT/mTOR signaling.

In conclusion, RvE1 protected against DOX-induced cardiotoxicity via the regulation of AKT/mTOR signaling. PMID: 32750329 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32750329?dopt=Abstract

Source: Biochemical Pharmacology - July 31, 2020 Category: Drugs & Pharmacology Authors: Zhang J, Wang M, Ding W, Zhao M, Ye J, Xu Y, Wang Z, Ye D, Li D, Liu J, Wan J Tags: Biochem Pharmacol Source Type: research