Acoustic-based chemical tools for profiling the tumor microenvironment.

Acoustic-based chemical tools for profiling the tumor microenvironment.
Curr Opin Chem Biol. 2020 Aug 05;57:114-121
Authors: Yadav AK, Hernandez S, Su S, Chan J
Abstract
Acoustic-based imaging modalities (e.g. ultrasonography and photoacoustic imaging) have emerged as powerful approaches to noninvasively visualize the interior of the body due to their biocompatibility and the ease of sound transmission in tissue. These technologies have recently been augmented with an array of chemical tools that enable the study and modulation of the tumor microenvironment at the molecular level. In addition, the application of ultrasound and ultrasound-responsive materials has been used for drug delivery with high spatiotemporal control. In this review, we highlight recent advances (in the last 2-3 years) in acoustic-based chemical tools and technologies suitable for furthering our understanding of molecular events in complex tumor microenvironments.
PMID: 32769068 [PubMed - as supplied by publisher]

Source: Current Opinion in Chemical Biology - August 4, 2020 Category: Biochemistry Authors: Yadav AK, Hernandez S, Su S, Chan J Tags: Curr Opin Chem Biol Source Type: research