A Pharmacokinetic Study of Methylphenidate Hydrochloride Multilayer Extended-Release Capsules (Aptensio XR ® ) in Preschool-Aged Children with Attention-Deficit/Hyperactivity Disorder
ConclusionThe PK of MPH-MLR in preschool children demonstrated the biphasic absorption profile described earlier in older children, and the PK profile in children with ADHD aged 4 to < 6 years was similar to the profile in those aged 6–11 years, apart from a lowerVd and relatively higher systemic MPH levels for children in the preschool group.Trial registrationClinicaltrials.gov Identifier: NCT02470234.
Source: Pediatric Drugs - Category: Pediatrics Source Type: research
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