Extent and prevalence of post-exercise and nocturnal hypoglycemia following peri-exercise bolus insulin adjustments in individuals with type 1 diabetes

Publication date: Available online 6 August 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Olivia McCarthy, Rachel Deere, Rachel Churm, Gareth J. Dunseath, Charlotte Jones, Max L. Eckstein, David M. Williams, Jennifer Hayes, Jason Pitt, Stephen C. Bain, Othmar Moser, Richard M. Bracken
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research

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Publication date: Available online 23 September 2020Source: Journal of Evidence Based Dental PracticeAuthor(s): Ting Liu, Yuan Wei, Yanan Zhu, Weidong Yang
Source: Journal of Evidence Based Dental Practice - Category: Dentistry Source Type: research
Conclusions. Human islet isolates with insufficient beta-cell mass for implantation within 72 hours can be cultured for 96 hours and longer to combine multiple preparations in order to reach the desired beta-cell dose and therefore result in a better metabolic benefit.
Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research
Delvac Oceandy Diabetes mellitus (DM) is one of the major causes of death in the world. There are two types of DM—type 1 DM and type 2 DM. Type 1 DM can only be treated by insulin injection whereas type 2 DM is commonly treated using anti-hyperglycemic agents. Despite its effectiveness in controlling blood glucose level, this therapeutic approach is not able to reduce the decline in the number of functional pancreatic β cells. MST1 is a strong pro-apoptotic kinase that is expressed in pancreatic β cells. It induces β cell death and impairs insulin secretion. Recently, a potent an...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
AbstractThe development of new diabetes treatment strategies has garnered much interest given that conventional management therapies for type 1 diabetes fail to provide optimal glycemic control while creating a high burden of self-care to patients. Stimuli-responsive, “closed-loop” systems are particularly attractive due to their ability to mimic dynamic ß cell function by releasing insulin in response to fluctuating glucose levels in real-time and with minimal patient discomfort. In this short review, we focus on stimuli-responsive, reservoir-based insulin delivery devices. We explore and evaluate system...
Source: Pharmaceutical Research - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 22 September 2020Source: Canadian Journal of DiabetesAuthor(s): Fried L, Chetty T, Cross D, Breen L, Davis E, Roby H, Jackiewicz T, Nicholas J, Jones T
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Patients with type 1 diabetes or type 2 diabetes had a significant higher mortality rate following kidney transplant compared with patients without diabetes, a large new analysis of US patients shows.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
(Flinders University) Adults conceived through sperm donation reported higher frequencies of allergies, type 1 diabetes and other autoimmune conditions. Donor sperm conceived adults had seven times more type 1 diabetes diagnoses; double the incidence of thyroid disease, acute bronchitis and sleep apnoea; and 10% more reported allergies. The study looked at 272 donor-conceived adult participants compared to 877 conceived naturally, from around the world with most from Australia, US, UK, Belgium and Netherlands.
Source: EurekAlert! - Biology - Category: Biology Source Type: news
Type 1 diabetes (T1D) is caused by immune-mediated destruction of the β-cells. After initiation of insulin therapy many patients experience a period of improved residual β-cell function leading to partial dise...
Source: BMC Pediatrics - Category: Pediatrics Authors: Tags: Research article Source Type: research
We report the case of an adult woman who developed T1DM and minimal ch...
Source: BMC Nephrology - Category: Urology & Nephrology Authors: Tags: Case report Source Type: research
Type 1 diabetes (T1D) is a lifelong disorder caused by an autoimmune reaction and the consequent destruction of pancreatic beta cells, leading to an absolute insulin deficiency in the body. To date, the only therapeutic option is insulin therapy, which is administered either as an MDI (multiple daily injection) or by means of an insulin pump [1].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
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