Relaxin Can Mediate Its Anti-Fibrotic Effects by Targeting the Myofibroblast NLRP3 Inflammasome at the Level of Caspase-1

ConclusionThe anti-fibrotic actions of RLX appear to require modulation of caspase-1 within the myofibroblast NLRP3 inflammasome.

Source: Frontiers in Pharmacology - August 3, 2020 Category: Drugs & Pharmacology Source Type: research