Melatonin against acute ischaemic stroke dependently via suppressing both inflammatory and oxidative stress downstream signallings.

In conclusion, TLR inflammatory and oxidative stress signallings played crucial roles for brain damage and impaired neurological function after IS that were significantly reversed by Mel therapy. PMID: 32729676 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32729676?dopt=Abstract

Source: J Cell Mol Med - July 29, 2020 Category: Molecular Biology Authors: Chen KH, Lin KC, Ko SF, Chiang JY, Guo J, Yip HK Tags: J Cell Mol Med Source Type: research