13q deletion syndrome resulting from balanced chromosomal rearrangement in father: the significance of parental karyotyping

Retinoblastoma is a malignancy of the eye in children characterized by biallelic inactivation of the retinoblastoma 1 gene (RB1), located at chromosome 13q14.2. Children with interstitial chromosome 13q deletions...

Source: Molecular Cytogenetics - July 23, 2020 Category: Molecular Biology Authors: Sabine Dittner-Moormann, Madlen Reschke, Eva Biewald, Alma Kuechler, Barbara Klein, Beate Timmermann, Dietmar Lohmann, Petra Ketteler and Deniz Kanber Tags: Case Report Source Type: research