Pain thresholds and intensities of CRPS type I and neuropathic pain in respect to sex

DiscussionPain thresholds in patients show only minor sex differences. However, these differences mimic those observed in healthy subjects and do not seem to be linked to specific pathophysiological processes.SignificanceFemale healthy participants and female patients with neuropathic pain conditions or CRPS I report lower pain thresholds compared to males, but pain intensity is similar and there is no sex difference in the extent to which the thresholds are altered in neuropathic pain or CRPS. Thus, the sex differences observed in various chronic pain conditions mimic those obtained in healthy participants, indicating that these differences are not linked to specific pathophysiological processes and are of minor clinical relevance.

Source: European Journal of Pain - June 10, 2020 Category: Anesthesiology Authors: Christine H. Meyer ‐Frießem, Nadine Attal, Ralf Baron, Didier Bouhassira, Nanna B. Finnerup, Rainer Freynhagen, Janne Gierthmühlen, Maija Haanpää, Per Hansson, Troels S. Jensen, Harriet Kemp, Donna Kennedy, Anne‐Sofie Leffler, Andrew Tags: ORIGINAL ARTICLE Source Type: research