Molecular regulation of the expression of leptin by hypoxia in human coronary artery smooth muscle cells

Conclusion:
Hypoxia in HCASMCs increases leptin expression through the induction of AngII, ROS, and the JNK pathway to enhance atherosclerosis in HCASMCs.

Source: Journal of Biomedical Science - January 9, 2015 Category: Biomedical Science Authors: Chiung-Zuan ChiuBao-Wei WangKou-Gi Shyu Source Type: research