A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children.

A literature review of 2019 novel coronavirus (SARS-CoV2) infection in neonates and children. Pediatr Res. 2020 Jul 17;: Authors: Di Nardo M, van Leeuwen G, Loreti A, Barbieri MA, Guner Y, Locatelli F, Ranieri VM Abstract At the time of writing, there are already millions of documented infections worldwide by the novel coronavirus 2019 (2019-nCoV or severe acute respiratory syndrome coronavirus 2 (SARS-CoV2)), with hundreds of thousands of deaths. The great majority of fatal events have been recorded in adults older than 70 years; of them, a large proportion had comorbidities. Since data regarding the epidemiologic and clinical characteristics in neonates and children developing coronavirus disease 2019 (COVID-19) are scarce and originate mainly from one country (China), we reviewed all the current literature from 1 December 2019 to 7 May 2020 to provide useful information about SARS-CoV2 viral biology, epidemiology, diagnosis, clinical features, treatment, prevention, and hospital organization for clinicians dealing with this selected population. IMPACT: Children usually develop a mild form of COVID-19, rarely requiring high-intensity medical treatment in pediatric intensive care unit. Vertical transmission is unlikely, but not completely excluded. Children with confirmed or suspected COVID-19 must be isolated and healthcare workers should wear appropriate protective equipment. Some clinical features (higher incidence of fever, vomi...
Source: Pediatric Research - Category: Pediatrics Authors: Tags: Pediatr Res Source Type: research