Bisphenol A induces Agrp gene expression in hypothalamic neurons through a mechanism involving ATF3.

Conclusions: Overall, these results indicate hypothalamic Agrp is susceptible to dysregulation by BPA and implicate ATF3 as a common mediator of the orexigenic effects of BPA in hypothalamic neurons.

https://www.karger.com/Article/FullText/509592

Source: Neuroendocrinology - June 22, 2020 Category: Endocrinology Source Type: research