Altered Epidermal Permeability Barrier Function in the Uninvolved Skin Supports a Role of Epidermal Dysfunction in the Pathogenesis of Occupational Hand Eczema

In conclusion, the uninvolved skin site of subjects with hand eczema exhibits abnormalities in epidermal perme ability barrier, supporting a pathogenic role of epidermal dysfunction in hand eczema. Whether subjects with hand eczema in other occupations also display altered epidermal function on uninvolved skin remains to be explored.Skin Pharmacol Physiol 2020;33:94 –101

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Source: Skin Pharmacology and Physiology - March 30, 2020 Category: Dermatology Source Type: research