Perfluorocarbons in Chemical Biology.

Perfluorocarbons in Chemical Biology.
Chembiochem. 2020 Jul 06;:
Authors: Miller MA, Sletten E
Abstract
Perfluorocarbons, saturated carbon chains where all the hydrogen atoms are replaced with fluorine, form a separate phase from both organic and aqueous solutions. Though perfluorinated compounds are not found in living systems, they can be used to modify biomolecules to confer orthogonal behavior within natural systems, such as improved stability, engineered assembly, and cell-permeability. Perfluorinated groups also provide handles for purification, mass-spectrometry, and 19 F NMR studies in complex environments. Herein, we describe how the unique properties of perfluorocarbons have been employed to understand and manipulate biological systems.
PMID: 32628804 [PubMed - as supplied by publisher]

Source: Chembiochem - July 5, 2020 Category: Biochemistry Authors: Miller MA, Sletten E Tags: Chembiochem Source Type: research