TMEM16A ameliorates vascular remodeling by suppressing autophagy via inhibiting Bcl-2-p62 complex formation

Conclusion: TMEM16A regulates the four-way interaction between p62, Bcl-2, Beclin-1, and VPS34, and coordinately prevents vascular autophagy and remodeling

Source: Theranostics - July 3, 2020 Category: Molecular Biology Authors: Xiao-Fei Lv, Ya-Juan Zhang, Xiu Liu, Hua-Qing Zheng, Can-Zhao Liu, Xue-Lin Zeng, Xiang-Yu Li, Xiao-Chun Lin, Cai-Xia Lin, Ming-Ming Ma, Fei-Ran Zhang, Jin-Yan Shang, Jia-Guo Zhou, Si-Jia Liang, Yong-Yuan Guan Tags: Research Paper Source Type: research