Nei Endonuclease VIII-like 2 Gene rs8191670 Polymorphism affects the Sensitivity of Non-small Cell Lung Cancer to Cisplatin by binding with MiR-548a

Conclusion: Our results demonstrated that NEIL2 gene rs8191670 polymorphism affects the PFS of advanced NSCLC patients, and the underlying molecular mechanisms may be that miR-548a can regulate NEIL2 expression by binding to its 3'UTR seed region containing rs8191670.

Source: Journal of Cancer - July 2, 2020 Category: Cancer & Oncology Authors: Wei He, Lina Pang, Shuai Gong, Xin Wang, Lixia Hou Tags: Research Paper Source Type: research