RCC2 Expression Stimulates ER-Positive Breast Tumorigenesis.

Conclusions: Our results suggest that estrogen-induced RCC2 expression prompts IGF1, TWIST1, and IL-6 expression, stimulates cell migration, and inhibits apoptosis to contribute to ER + breast tumorigenesis. PMID: 32565805 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/32565805?dopt=Abstract

Source: Journal of Oncology - June 24, 2020 Category: Cancer & Oncology Tags: J Oncol Source Type: research