Infant blood lipids: a systematic review of predictive value and influential factors.

Infant blood lipids: a systematic review of predictive value and influential factors. Expert Rev Cardiovasc Ther. 2020 Jun 13;: Authors: Felzer-Kim IT, Visker JP, Ferguson D, Hauck JL Abstract INTRODUCTION: Blood lipid screening recommendations begin at ages 9 - 11 years, despite poor adherence and evidence of fatty streaks in coronary arteries by 3-years of age. For cardiovascular disease (CVD) prevention, there may be value in earlier measurement of blood lipids. AREAS COVERED: The present systematic review examines evidence concerning total cholesterol, low-density lipoprotein, high-density lipoprotein, and triglycerides during the infant period. Included are studies examining the extent to which infant blood lipids predict later values in childhood and factors that influence their magnitude. A total of 38 articles (published from 1965 to 2013) met inclusion criteria and were examined in this review. EXPERT OPINION: Longitudinal data suggests correlative relationships in all lipid values around 6 months of age, except for TRG. Influential factors related to blood lipids in infancy include sex, race, family history, feeding, gestational length, birth weight, and maternal factors. Clinical measurement of infant lipids could perhaps provide an early marker of CVD and a target of early CVD prevention strategies. The identification of personal characteristics that associate with high or low values in each lipid could be...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research