Molecular analysis confirms retinoblastoma diagnosis in a histologically undifferentiated retinal tumor in an adult.
We present a case of a white retinal tumor in a 42-year-old woman that progressed slowly over 3 years and on enucleation an undifferentiated tumor was found without a conclusive diagnosis. Molecular analysis identified RB1 pathogenic variant that confirmed retinoblastoma diagnosis in this discordant clinicopathologic presentation of the tumor.
PMID: 32543965 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
More News: Cancer | Cancer & Oncology | Eye Cancers | Genetics | Opthalmology | Pediatrics | Retinoblastoma | Undifferentiated Carcinoma | Vitamin A