Attention and executive function are impaired during active standing in postural tachycardia syndrome.

Attention and executive function are impaired during active standing in postural tachycardia syndrome. Auton Neurosci. 2020 Jun 06;227:102692 Authors: Miller AJ, Sheehan T, Bourne KM, Feeley M, Arnold AC Abstract Postural tachycardia syndrome (POTS) is a chronic form of orthostatic intolerance associated with cognitive dysfunction. We hypothesized executive function and attention is impaired in POTS during active standing. Eighty-seven POTS participants and 39 healthy controls of similar age, sex, and education level completed executive function (Stroop word-color) and attention (CogState Identification) tests in supine and standing postures in a cross-sectional study. POTS participants had lower executive function (t-score: 48 ± 11 vs. 55 ± 10 control; p = 0.009) and worse attention (reaction speed: 2.78 ± 0.11 vs. 2.69 ± 0.06 control; p < 0.001) during standing. These data provide new evidence that active standing impairs attention and executive functioning in POTS. PMID: 32526639 [PubMed - as supplied by publisher]
Source: Autonomic Neuroscience - Category: Neuroscience Authors: Tags: Auton Neurosci Source Type: research