Evaluation of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: A Pilot, Dose-Ranging, Randomized Study

ConclusionEach IBU/APAP FDC provided analgesic efficacy comparable to that with ibuprofen 400 mg and superior to that with placebo. Each FDC provided MPR in < 1 h, duration of pain relief > 9 h, and tolerability similar to that with ibuprofen and placebo.ClinicalTrials.gov RegistrationNCT01559259

http://link.springer.com/10.1007/s40268-020-00310-7

Source: Drugs in R&D - June 5, 2020 Category: Drugs & Pharmacology Source Type: research