Targeted sensitization of tumor cells for radiation through monocarboxylate transporters 1 and 4 inhibition in vitro

ConclusionsInhibition of MCT, especially MCT4 may represent a possible tool to overcome radiation resistance in tumor cell lines.Clinical relevanceMCT Inhibitors may be used as a possible therapeutic approach to sensitize OSCC to radiation.

http://link.springer.com/10.1007/s00784-020-03364-8

Source: Clinical Oral Investigations - June 2, 2020 Category: Dentistry Source Type: research