Third time's a charm? Mobilization of autologous peripheral blood stem cells in patients with two previous failed mobilizations with plerixafor.

CONCLUSIONS: The majority (73.3%) of patients who underwent three mobilization attempts were eventually able to collect enough cells to permit autologous transplantation. Extremely low peripheral blood CD34+ count after the first dose of plerixafor and collection yields during the first two attempts were associated with a poor collection yield on the third attempt. The risks and benefits of a third mobilization should be weighed to facilitate judicious use of resources. PMID: 32483875 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32483875?dopt=Abstract

Source: Transfusion - May 31, 2020 Category: Hematology Authors: Zhuang L, Boriboonnangkul P, Wang S, Yuan S Tags: Transfusion Source Type: research