MicroRNA miR-212 regulates PDCD4 to attenuate A β25-35-induced neurotoxicity via PI3K/AKT signaling pathway in Alzheimer's disease.

CONCLUSION: All the data in this study revealed that miR-212 modulated PDCD4 to regulate cell proliferation, apoptosis through PI3K/AKT signaling pathway in Aβ25-35-treated SH-SY5Y and IMR-32 cells, and this new regulatory network may provide a novel mechanism of AD. PMID: 32474742 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32474742?dopt=Abstract

Source: Biotechnology Letters - May 29, 2020 Category: Biotechnology Authors: Wang Y, Chang Q Tags: Biotechnol Lett Source Type: research