Sa1310 DO PROTON PUMP INHIBITORS DECREASE THE RISK OF RESPIRATORY TRACT CANCERS IN PATIENTS WITH BARRETT ’S ESOPHAGUS?

Several studies reported an increase in lung and laryngeal cancers in patients with gastroesophageal reflux disease (GERD). The underlying mechanism is thought to be damage to the respiratory epithelium by gastric refluxate causing lung injury, chronic inflammation, and cancer promotion by activating proliferative signal pathways. Barrett ’s Esophagus (BE) is a manifestation of severe GERD. So, we wanted to examine the prevalence of respiratory cancers in BE patients and evaluate any predisposing factors.

Source: Gastrointestinal Endoscopy - May 31, 2020 Category: Gastroenterology Authors: Vedha Sanghi, Mythri Anil Kumar, Motasem Alkhayyat, Madhusudhan R. Sanaka, Robert Butler, John R. Goldblum, John McMichael, Prashanthi N. Thota Tags: Poster abstracts Source Type: research