Viruses, Vol. 12, Pages 592: Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes

In conclusion, in infected hepatocytes, HBV passively evades recognition by cellular sensors of nucleic acids by (i) producing non-immunostimulatory RNAs, (ii) avoiding sensing of its DNAs by cGAS/STING without active inhibition of the pathway.

Source: Viruses - May 28, 2020 Category: Virology Authors: Lise Lauterbach-Rivi ère Ma ïwenn Bergez Saskia M önch Bingqian Qu Maximilian Riess Florian W. R. Vondran Juliane Liese Veit Hornung Stephan Urban and Renate K önig Tags: Article Source Type: research