Get ready for the latest science in heart failure
(European Society of Cardiology) Save the date for HFA Discoveries, the latest scientific platform of the European Society of Cardiology (ESC). Find out what's on the horizon for prevention and treatment during this innovative online event.Worldwide, an estimated 26 million people have heart failure.1 In Europe, one-year all-cause mortality rates for acute and chronic heart failure are 23.6% and 6.4%, respectively, and heart failure hospitalisation rates are 18.7% and 9.9%, respectively.
Condition: Chronic Systolic Heart Failure Interventions: Drug: Recombinant human Neuregulin for injection; Drug: Placebo Sponsor: Zensun Sci. & Tech. Co., Ltd. Not yet recruiting
Conclusion: Prophylactic ligature of high-flow AV fistulas after kidney transplantation can avoid high-output heart failure, and a more liberal approach to close AV fistulas might be justified.Am J Nephrol
Conclusion: The risk of severe maternal cardiac complications during pregnancy in women with congenital heart disease is low. In this largest analysis to date with a focus on parity in 307 women, the risk classification predicts the maternal outcome more than parity per se. If the first pregnancy is uneventful, the OR is 5.5 for an uneventful second pregnancy if CARPREG I and mWHO scores remain unchanged.Cardiology
In this study, we investigated the effects of how HF-induced atrial cellular electrophysiological (with prolonged AP duration) and tissue stru ctural (reduced cell-to-cell coupling caused by atrial fibrosis) remodelling can have an effect on the generation of atrial AP alternans and their conduction at the cellular and one-dimensional (1D) tissue levels. Simulation results showed that HF-induced atrial electrical remodelling prolonged AP d uration, which was accompanied by an increased sarcoplasmic reticulum (SR) Ca2+ content and Ca2+ transient amplitude. Further analysis demonstrated that HF-induced atrial electrical remo...
Publication date: September 2020Source: American Heart Journal, Volume 227Author(s): Diego Araiza-Garaygordobil, Rodrigo Gopar-Nieto, Pablo Martinez-Amezcua, Alejandro Cabello-López, Gabriela Alanis-Estrada, Abraham Luna-Herbert, Héctor González-Pacheco, Cynthia Paola Paredes-Paucar, Martinez Daniel Sierra-Lara, Jose Luis Briseño-De la Cruz, Hugo Rodriguez-Zanella, Marco Antonio Martinez-Rios, Alexandra Arias-Mendoza
This study highlighted the importance of implementing a short screening procedure in hospitals dealing with cardiovascular inpatients to identify those individuals who require specific attention and interventions.
ConclusionOld age, heart failure, and lower platelet counts affected heparin activity. The dose of heparin should be considered in those patients to reach the target ACT.
AbstractChildren with ventricular septal defects (VSDs) are subjected to hemodynamic overload which causes myocardial injury and subsequent heart failure. Early stages of myocardial damage cannot be detected by conventional echocardiography. Two-dimensional speckle tracking echocardiography (2D-STE) and cardiac troponin I (cTnI) have been recently introduced as more accurate tools for early assessment of cardiovascular diseases. The purpose of this study is to evaluate the role of cardiac troponin I (cTnI) and 2D-STE in the early detection of VSD-induced myocardial injury. Thirty children with VSD (symptomatic and asymptom...
We report the successful endovascular repair of a rare case of aortic rupture caused by axillary intra ‐aortic balloon pump (IABP) insertion failure. A 38‐year‐old Jehovah's Witness female with situs inversus totalis was referred to our hospital for acute decompensated heart failure. We placed an axillary IABP for circulatory support. However, an exchange was required due to balloon malfunction (kinked driveline). Unfortunately, the exchange was complicated by an iatrogenic aortic rupture along with a large hematoma compressing the trachea. Emergent endovascular repair was performed successfully without any blood tra...
ConclusionsWith the continuing miniaturization of pump designs, less invasive, more durable and cost ‐effective pumps have become available for dual assist device therapy in in these critically ill heart failure patients.