The circular RNA TLK1 exacerbates myocardial ischemia/reperfusion injury via targeting miR-214/RIPK1 through TNF signaling pathway.

CONCLUSION: Taken together, our study revealed an up-regulated circRNA, circTLK1, could exacerbate myocardial IRI via targeting miR-214/RIPK1-mediated TNF signaling pathway, which may provide therapeutic targets for treatment. PMID: 32445866 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32445866?dopt=Abstract

Source: Free Radical Biology and Medicine - May 19, 2020 Category: Biology Authors: Song YF, Zhao L, Wang BC, Sun JJ, Hu JL, Zhu XL, Zhao J, Zheng DK, Ge ZW Tags: Free Radic Biol Med Source Type: research

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