Shadows Behind Using Simple Risk Models in Selection of Hepatocellular Carcinoma Patients for Liver Transplantation
Objective:
To assess the potential influence of replacing Milan criteria with simple risk scores on outcomes of hepatocellular carcinoma (HCC) patients undergoing liver transplantation.
Summary Background Data:
Several risk scores combining morphological and biological features were recently proposed for precise selection of HCC patients for transplantation.
Methods:
This retrospective study included 282 HCC liver transplant recipients. Recurrence-free survival (RFS), the primary outcome measure, was evaluated according to Metroticket 2.0 model and French AFP model with Milan criteria serving as benchmark.
Results:
Patients were well stratified with respect to RFS by Milan criteria, Metroticket 2.0 criteria, and AFP model cut-off ≤2 points (all P
Source: Annals of Surgery - Category: Surgery Tags: ORIGINAL ARTICLES Source Type: research
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