Oligodendrocyte ARNT2 expression is altered in models of MS

Conclusion
The analysis of ARNT2 expression in OLs demonstrates that OL ARNT2 expression is altered in EAE and during OL maturation. Findings point to ARNT2 as an important mediator of OL viability and differentiation and warrant further characterization as a target for intervention in demyelinating disorders such as MS.

Source: Neurology Neuroimmunology and Neuroinflammation - May 20, 2020 Category: Neurology Authors: Becquart, P., Johnston, J., Vilarino-Güell, C., Quandt, J. A. Tags: All Immunology, Autoimmune diseases, Multiple sclerosis Article Source Type: research