High potential of SOX21 gene promoter methylation as an epigenetic biomarker for early detection of colorectal cancer

Conclusion: The results of this study indicated the high potential of SOX21 gene promoter methylation as a candidate noninvasive diagnostic biomarker in stool and plasma of colorectal cancer patients. However, further studies with larger sample sizes are required to evaluate the specific role of SOX21 methylation as a biomarker for early detection of CRC.

Source: Indian Journal of Cancer - May 17, 2020 Category: Cancer & Oncology Authors: Keivan Moradi Esmaeil Babaei Nayebali Rezvani Reza Safaralizadeh Homayoun Bashiri Mohammad Ali Hosseinpour Feizi Source Type: research