Activation of the alternative complement pathway predicts renal outcome in patients with lupus nephritis.

CONCLUSION: This study showed that there was alternative complement pathway limited activation in the renal tissue in a small number of patients with LN, and these patients had worse renal outcomes compared to patients with glomerular classical complement pathway activation with or without alternative pathway activation. PMID: 32408850 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32408850?dopt=Abstract

Source: Lupus - May 13, 2020 Category: Rheumatology Authors: Kim H, Kim T, Kim M, Lee HY, Kim Y, Kang MS, Kim J Tags: Lupus Source Type: research