Cinnamomi Cortex and Scutellariae Radix in the Japanese herbal medicine Kampo saireito inhibit expression of iNOS through different mechanisms in hepatocytes

ConclusionCinnamomi Cortex and Scutellariae Radix can prevent the induction of iNOS gene expression, in part through NF ‐κB activation and IL‐1RI upregulation with different mechanisms, indicating that saireito containing both crude drugs may be a potential therapeutic treatment for injured livers.

Source: Traditional and Kampo Medicine - March 31, 2020 Category: Complementary Medicine Authors: Hideyuki Matsushima, Hidehiko Hishikawa, Hirokazu Miki, Masahiko Hatta, Richi Nakatake, Tadayoshi Okumura, Mikio Nishizawa, Masaki Kaibori, Mitsugu Sekimoto Tags: ORIGINAL ARTICLE Source Type: research