Dynamic State of Water Molecular Displacement of the Brain during the Cardiac Cycle in Idiopathic Normal Pressure Hydrocephalus

Normal pressure hydrocephalus (NPH) has been characterized as a chronic communicating hydrocephalus in elderly patients with the clinical triad gait disturbance, dementia, and incontinence [1–3]. The clinical symptoms of both secondary and idiopathic NPH (iNPH) can be reversed by the removal of the accumulated cerebrospinal fluid (CSF) [3]. Secondary NPH can result in subarachnoid hemorrhage, trauma, and stroke. Although numerous investigations have attempted to clarify the underlying mechanism of and to diagnose iNPH, its exact causes remain poorly understood.

Source: Computerized Medical Imaging and Graphics - January 6, 2015 Category: Radiology Authors: Hirohito Kan, Tosiaki Miyati, Mitsuhito Mase, Tomoshi Osawa, Naoki Ohno, Harumasa Kasai, Nobuyuki Arai, Makoto Kawano, Yuta Shibamoto Source Type: research