Hypopituitarism in five PROP1 mutation siblings: long-lasting natural course and the effects of growth hormone replacement introduction in middle adulthood

This report provides important experience regarding hormonal replacement, particularly rhGH treatment, in adults with long-term untreated CH. Beneficial effect of such therapy are widely acknowledged, yet these subjects could be susceptible to certa in risks of hormonal treatment initiated in adulthood. Careful and continual clinical follow-up is thus strongly advised.
Source: Pituitary - Category: Endocrinology Source Type: research