Secondhand cigarette smoke induces increased expression of contractile endothelin receptors in rat coronary arteries via a MEK1/2 sensitive mechanism.

Conclusions: Taken together, our data show that SHS increases contractile ET receptors and MEK1/2 pathway inhibitor offsets SHS exposure-induced ETA and ETB receptor upregulation in rat coronary arteries. PMID: 32400208 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/32400208?dopt=Abstract

Source: Scandinavian Cardiovascular Journal - May 15, 2020 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research