LncRNA LINC00313 Knockdown Inhibits Tumorigenesis and Metastasis in Human Osteosarcoma by Upregulating FOSL2 through Sponging miR-342-3p.

CONCLUSION: LINC00313 is upregulated in OS, and LINC00313 knockdown plays a vital anti-tumor role in OS cell progression through a miR-342-3p/FOSL2 axis. Our study suggests that LINC00313 may be a novel, promising biomarker for diagnosis and prognosis of OS.
PMID: 32390359 [PubMed - in process]

Source: Yonsei Medical Journal - April 30, 2020 Category: Universities & Medical Training Authors: Chen H, Wahafu P, Wang L, Chen X Tags: Yonsei Med J Source Type: research